I had problems installing Adobe Creative Suite 3 on Windows Vista Home Premium. After reading a few pages, I found a solution. I had to reinstall Adobe Flash and Reader, but it worked for me.
From the bottom of the page at http://www.vistax64.com/vista-general/88734-adobe-cs3-installation.html:
[1] Install Microsoft Windows Installer CleanUp Utility from
http://support.microsoft.com/kb/290301
[2] Run the CS3Clean script from
http://www.adobe.com/support/contact/cs3clean.html.
Select the [undocumented] level 4 cleanup. This removes ALL Adobe
applications.
[3] Turn on User Account Control - may not be necessary, but it is for Adobe
Reader!
[4] Copy the Adobe CS3 folder to your HD, right-click Setup and select Run
As Administrator